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ORIGINAL ARTICLE
Retrospective Analysis of the Final Diagnosis of the Suspected Cases of Autochthonous Dengue Fever
Disease Control and Prevention Center, National Center for Global Health and Medicine
Koh SHINOHARA, Satoshi KUTSUNA, Yasuyuki KATO, Kei YAMAMOTO, Yoshihiro FUJIYA, Momoko MAWATARI, Nozomi TAKESHITA, Kayoko HAYAKAWA, Shuzo KANAGAWA & Norio OHMAGARI
(Received January 5, 2017)
(Accepted June 30, 2017)
Key words: dengue fever, domestic infection
Abstract

Background: In 2014, an outbreak of autochthonous Dengue Fever (DF) occurred in Japan. However, there are insufficient data on the diagnostic approach when we suspect infection with DF.

Methods: We defined autochthonous DF suspected cases as; I) Patients without any foreign travel history in the previous three months, and II) Patients who were referred from another hospital for the purpose of further examination for DF, or patients who visited our hospital expecting an examination for DF. Clinical and laboratory data were collected from the medical records of the "autochthonous DF suspected cases" who visited the travel clinic of the National Center for Global Health and Medicine, Tokyo, Japan, from 25th August to 26th September, 2014.

Results: Forty-seven patients were included for this study. Nine cases were diagnosed as having DF. Mosquito bite history, history of travel to endemic areas, decreased white blood cell count, and decreased platelet count were statically significant risk factors for DF. Among non-DF cases, nine cases with bacterial infections and six hospitalized cases were included.

Conclusion: The majority of the final diagnoses of autochthonous DF suspected cases were common febrile illnesses, however, there were some bacterial infections and severe cases. Mosquito bite history, history of travel to endemic areas, decreased white blood cell count, and decreased platelet count will be useful for differentiation among DF cases and non-DF cases.

[ Kansenshogaku Zasshi 91: 930-935, 2017 ]

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