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Effect of the Change in Antiseptic from 10% Povidone-iodine to 1% Chlorhexidine-alcohol on Bacterial Contamination in Blood Culture
1)Department of Emergency Medicine and Intensive Care Medicine, Otsu City Hospital, 2)Microbiology Laboratory, Good Life Design Inc., 3)Department of Emergency Medicine, Toyota Memorial Hospital, 4)Department of Intensive Care Medicine, Toyota Memorial Hospital, 5)Department of Infectious Disease, Toyota Memorial Hospital
Hiroyuki OTE1), Yoshiko SUGAKI2), Yoshitomo NISHIKAWA3), Jintetsu MINAMI4) & Atsushi KAWABATA5)
(Received July 3, 2017)
(Accepted October 30, 2017)
Key words: blood culture, contamination rate, chlorhexidine-alcohol

Skin preparation for phlebotomy with 10% povidone-iodine requires 2 minutes for antisepsis. In cases of blood sampling from the vein for blood culture, waiting for 2 minutes has not necessarily been maintained in the Toyota Memorial Hospital. Accordingly, the hospital changed the antiseptic from 10% povidone-iodine to 1% chlorhexidine-alcohol that has a rapid sterilizing effect. After changing, a detection of coagulase negative staphylococci, a contaminating bacteria, in the culture bottle significantly decreased from 2.96% to 1.65% (p<0.0001) throughout the hospital. The decrease rate was not significantly different between the wards including the intensive care unit and the outpatient department including the emergency room. These findings indicate that 1% chlorhexidine-alcohol should be used for sterilizing the skin in blood sampling for blood culture through in all hospital departments.

[ Kansenshogaku Zasshi 92: 46-50, 2018 ]

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