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A Case of Helicobacter cinaedi Isolated from Inflammatory Intestinal Mucosa Following Bacteremia with Diffuse Large B-cell Lymphoma
1)Department of Clinical Laboratory, Shiga General Hospital, 2)Department of Haematology and Oncology, Shiga General Hospital
Hisaaki NISHIO1) & Kohsuke ASAGOE2)
(Received May 25, 2017)
(Accepted November 7, 2017)
Key words: Helicobacter cinaedi, bacteremia, malignant lymphoma

A 79-year-old woman with diffuse large B-cell lymphoma (DLBCL), who had undergone R-DeVIC therapy, was admitted to our hospital because of cellulitis. After the cellulitis was healed, she was treated with the oral administration of etoposide for DLBCL.

On day 22, she was administered ceftriaxone for bacteremia accompanied by high fever;when blood culture was positive for Helicobacter cinaedi. On day 28, infectious enteritis due to Clostridium difficile with bloody stool appeared, and H. cinaedi was detected in the intestinal mucosa obtained by colonoscopy. Histopathological examination revealed gram-negative bacteria with a log spiral structure that is characteristic of H. cinaedi.

The presence of bowel lesions needs to be confirmed, when H. cinaedi bacteremia recurs.

[ Kansenshogaku Zasshi 92: 133-137, 2018 ]

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