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A Case of IgA Vasculitis Complicated with Multiple Abscesses Due to Staphylococcus aureus
Department of General Medicine, Kagoshima Seikyo Hospital
Hiroki YAMAKUCHI, Masanari KOMATSU & Hiroko SAEKI
(Received February 21, 2018)
(Accepted April 20, 2018)
Key words: IgA vasculitis, Staphylococcus aureus, Staphylococcal enterotoxin

A 69-year-old woman received a diagnosis of multiple abscesses. Abscess drainage was performed, and methicillin-susceptible Staphylococcus aureus was isolated from blood and pus cultures. On post-operative day 4, she developed proteinuria and haematuria. She also complained of abdominal pain, and areas of purpura were seen over her extremities. CT scans showed ascites and ileum wall thickening. Leukocytoclastic vasculitis was observed on skin biopsy. Findings on renal biopsy were compatible Immunoglobulin A(IgA) nephropathy, therefore we diagnosed her illness as IgA vasculitis. She recovered following administration of antibiotics and steroids. The genes encoding for staphylococcal enterotoxin E and staphylococcal toxic shock syndrome toxin-1 were detected on the pathogen. Staphylococcal enterotoxins might have been involved in the pathogenesis of IgA vasculitis. Clinicians should bear IgA vasculitis in mind if patients with S. aureus infection develop abdominal pain, urine abnormality, and purpura.

[ Kansenshogaku Zasshi 92: 552-555, 2018 ]

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