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CASE REPORT
Severe Legionella Pneumonia Caused by Legionella pneumophila Serogroup 8 Diagnosed Using Loop-mediated Isothermal Amplification (LAMP): A Case Report
1)Department of Emergency and Critical Care Medicine, Kishiwada Tokushukai Hospital, 2)Department of Laboratory Medicine, Kishiwada Tokushukai Hospital, 3)Osaka Institute of Public Health, Division of Microbiology, Bacteriology Section
Wataru SHIRASAKA1), Chieko KUSHIBIKI2) & Chihiro KATSUKAWA3)
(Received November 15, 2017)
(Accepted June 29, 2018)
Key words: Legionella pneumonia, urinary antigen test, LAMP
Abstract

Legionella pneumonia can rapidly progress, therefore early diagnosis and treatment are important. The urinary antigen test (UAT) is a simple, easy, and useful diagnostic tool that is widely used; however, the UAT can only detect Legionella pneumonia caused by Legionella pneumophila serogroup 1. Alternatively, loop-mediated isothermal amplification (LAMP) of genetic material is a quick, simple,and accurate method to detect many species of the Legionella genus and its serotypes. Widespread use of LAMP is recommended. Herein, we describe a case of severe pneumonia caused by Legionella pneumophila serogroup 8 which demonstrates negative UAT results, but positive LAMP results.

[ Kansenshogaku Zasshi 92: 701-704, 2018 ]

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