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A Case of Bacteremia Caused by Rhodococcus corynebacterioides in a Patient with Cerebral Infarction
1)Department of Neurology, Showa General Hospital, 2)Department of Infectious Disease, Showa General Hospital, 3)Clinical Laboratory, Showa General Hospital, 4)Department of Infectious Disease, Tokyo Women's Medical University
Eri FUKAO1), Toshimi ODA2), Yutaka HONMA1), Kei OGINO2), Takayuki YOKOZAWA3) & Ken KIKUCHI4)
(Received May 10, 2019)
(Accepted July 12, 2019)
Key words: bacteremia, Rhodococcus corynebacterioides

We report herein on a case of bacteremia caused by Rhodococcus corynebacteroides in a 77 year-old woman who was under medical treatment in hospital for cerebral infarction. She had a high fever (41.3°C) on day 8 of her hospitalization and two sets of blood cultures yielded Gram-positive rods finally identified as R. corynebacterioides by 16S rRNA gene sequencing. After administration of tazobactam/piperacillin (TAZ/PIPC) her fever rapidly abated, and the inflammatory reaction also became negative. On the 11th day, antibiotics were de-escalated to cefazolin (CEZ) following the results of the susceptibility test. After confirming the negative blood culture results, antibiotic therapy was completed on the 17th day. Infectious exacerbation was not observed, and the patient's clinical course was uneventful.

The genus Rhodococcus is mostly non-pathogenic and inhabits in environments, such as soil and groundwater. R. corynebacterioides was isolated and identified as the causative agent of bacteremia in the current case study, has been reported only once in the past and thus ours would be a remarkably rare case.

[ Kansenshogaku Zasshi 93: 759-762, 2019 ]

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